“During the 20 years since our first study, the amount of plastic in our oceans has increased by around 50%, only further emphasizing the pressing need for action,” said one leading researcher.

Some of the key scientists who first informed the world of the potential damage being done to natural systems by microplastics are now calling for world leaders to take decisive action to curb the introduction of these polluting materials into the environment—and they hope the looming United Nations treaty process on plastics can be a key vehicle for progress.

Alongside a new scientific review published cataloging the growing body of research on microplastics—defined as plastic particles smaller than 5 millimeters and “composed of polymers together with functional additives as well as other intentionally and unintentionally added chemicals”—the international group of scientists says concerted actions must be taken, including bans on certain materials and a focus on plastic pollution mitigation that puts less emphasis on consumer habits and recycling efforts by keeping microplastics out of the supply chain “in the first place.”

According to the abstract of the review, published Thursday in the journal Science:

Twenty years after the first publication using the term microplastics, we review current understanding, refine definitions and consider future prospects. Microplastics arise from multiple sources including tires, textiles, cosmetics, paint and the fragmentation of larger items. They are widely distributed throughout the natural environment with evidence of harm at multiple levels of biological organization. They are pervasive in food and drink and have been detected throughout the human body, with emerging evidence of negative effects. Environmental contamination could double by 2040 and widescale harm has been predicted. Public concern is increasing and diverse measures to address microplastics pollution are being considered in international negotiations. Clear evidence on the efficacy of potential solutions is now needed to address the issue and to minimize the risks of unintended consequences.

Professor Richard Thompson of Plymouth University, who co-authored that first scientific study and coined the term microplastics just two decades years ago, says researchers now have more than enough evidence to show world leaders that serious action must be taken to curb the use of plastics, with special attention to the minuscule and microscopic forms of the material that are increasingly being found polluting ecosystems—both on land as well as in the sea—and embedded within living organisms, including humans.

“There are still unknowns, but during the 20 years since our first study, the amount of plastic in our oceans has increased by around 50%, only further emphasizing the pressing need for action,” Thompson said in a statement put out by Plymouth.

In the statement, the university noted:

Since the publication of the first study in 2004, an estimated 7,000 research studies have been conducted on microplastics, providing considerable evidence in their sources and impacts as well as potential solutions.

Microplastics have been found on every corner of the planet, in more than 1,300 aquatic and terrestrial species, in the food and drink we consume, and in multiple tissues and organs of the human body.

With emissions of microplastics to the environment estimated to be up to 40 megatons per year, a number that could double by 2040, predictions indicate the potential for widescale environmental harm moving into the next century.

The research details how microplastics demand an international response due to their transitory nature. While they enter the environment in various ways—whether from direct release as fibers into the air from textiles or dust, discharged through water systems via runoff or sewage drains, or via breakdown or fragmentation—once discarded, the study says, “microplastics can travel far from their point of entry and are not constrained by national boundaries highlighting the importance of actions at a global level.”

Professor Sabine Pahl, who teaches Urban and Environmental Psychology at the University of Vienna and is an honorary professor at the University of Plymouth, said, “Plastic pollution is completely caused by human actions. That’s why we need research on perceptions of risks and benefits of plastic as well as other drivers of policy support and change, integrating a social science perspective.”

With the next round of talks in the UN’s Plastic Pollution Treaty set for November, the researchers said the negotiations offer a “tangible opportunity” for nations to act on this issue. “In our view,” they wrote, “science will be just as important guiding the way toward solutions as it has been in identifying the problems.”

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  action, microplastics, pollution, scientists